| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32a40218af13a451d5cb407368118bdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9de29a36113ab76f0710c0740a824b61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adb97ae84b91a4d6eeb65d489c4a0dc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605 |
| filingDate |
2007-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af3c6ecd43cd938c87055d768fb6b491
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95c13c9fd2db5351a6426c0d7b2f9c0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8eb49fecb6f75749e42a40a3006730f |
| publicationDate |
2007-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007147816-A1 |
| titleOfInvention |
Insulinotropic peptide synthesis |
| abstract |
The present invention relates to the preparation of insulinotropic peptides that are synthesized using a solid and solution phase ('hybrid') approach. Generally, the approach includes synthesizing three different peptide intermediate fragments using solid phase chemistry. Solution phase chemistry is then used to add additional amino acid material to one of the fragments. The fragments are then coupled together in the solid solution phase. The use of a pseudoproline in one of the fragments eases solid phase synthesis of that fragment and also eases subsequent solution phase coupling of this fragment to other fragments. The present invention is very useful for forming insulinotropic peptides such as GLP-1(7-36) and its natural and non-natural counterparts. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019170918-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012525348-A
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009053315-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014077802-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10954267-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012084754-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020074583-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104011064-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016046753-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11459354-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014077801-A1 |
| priorityDate |
2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |