http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007145467-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa4ca341eea780a19ee33a8922ab2507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259045c6eba6e2c5d338b84e0a88b571 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d7e8ec983d08a5c17eefc375f0560e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d343e167689068bd7cbe93e640dd82a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15c3c89e7483f8baaf585dce144df6c9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-39 |
| filingDate | 2007-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceaa6cbeb24abfebe355ac3d5f77675c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65902fbadbc1f05466be1fdf25a92740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9016eba29d0c2e952cc3df9a2863f76d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49089889f6018e077e52ca4f2203b490 |
| publicationDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2007145467-A1 |
| titleOfInvention | A novel gene from hancenula polymorpha capable of controlling unfolded protein response and method for increasing effect of secretion using the same |
| abstract | The present invention relates to a novel H. polymorpha gene regulating Unfolded Protein Response (UPR) and a method for improving the efficiency of secretory expression of a recombinant protein using the same, more particularly, a method for improving the efficiency of secretory expression of a recombinant protein by identifying, modifying, and optimizing the HpHACl gene, which encodes a key transcription regulatory factor of the UPR mechanism in H. polymorpha, and a regulatory mechanism mediated by the gene. According to the present invention, the secretory expression system of H. polymorpha can be used for the mass-production of secretory proteins for industrial and medical applications, thereby producing a large amount of the proteins at low cost. Accordingly, the method is employed in the production of the proteins for industrial and medical use, so as to reduce economic burden for a patient, and contribute to the improvement in the welfare of all mankind. |
| priorityDate | 2006-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 475.