Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86d5412d1ff0603847ead581bdf91d5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78e6ca3769e36b4cbf31e8c55fbb1e24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9aee068a7beee575b004f6fd79c56feb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_424761268f2d29e5cb70aa13e5a0ef36 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-43 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573 |
filingDate |
2007-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a04f8708e08fb14f94df3449ef1984e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49c87b5d324db96f64842c8f3658360e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14fe2e8526bb5200783fdca9e4a15913 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d00352ac00eb1bd10ed5bb7a99e44450 |
publicationDate |
2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007137294-A2 |
titleOfInvention |
Dexamethasone-eluting endoprosthesis to promote human coronary artery endothelial cell migration |
abstract |
A drug-eluting endoprosthesis is configured for inhibiting restenosis and thrombosis, and for promoting healing of a lesion in a body of a subject. Such an endoprosthesis includes at least a supporting structure and a therapeutically effective amount of dexamethasone is disposed thereon. The therapeutically effective amount of dexamethasone allows for the drug to elute from the supporting structure so as to obtain a concentration of dexamethasone that is sufficient for inhibiting restenosis and/or inhibiting thrombosis. Also, the therapeutically effective amount of dexamethasone is substantially devoid of inhibiting cell migration such that migrating cells promote healing of the lesion. Additionally, the therapeutically effective amount of dexamethasone induces cell migration such that migrating cells promote healing of the lesion. |
priorityDate |
2006-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |