| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b0fe3146faca2de8a84856ba2074594
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6e7cd8bd32e6d0dc5c183525c2ec2f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_280d87031f0c5786de1808713a1b76b7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 |
| filingDate |
2007-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed13b04b67b7220980640616bcc20345
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11d1ed50cc87d8b9d29779e9e669c153 |
| publicationDate |
2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007137000-A2 |
| titleOfInvention |
Combination cancer chemotherapy |
| abstract |
Provided is a method for improving treatment of a neoplastic condition by combining a therapeutically effective amount of a polyADP-ribose polymerase inhibitor with a therapeutically effective amount of a compound which triggers the release of nucleolin from the G-quadruplexes in rDNA. As specifically exemplified, the compound which increases nucleolin binding is a substituted quinobenzoxazine analog, for example CX-3543. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9078888-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9604931-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011178704-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9623021-B2 |
| priorityDate |
2006-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |