| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ebd16823f67394b9ff786717b0e2c25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efbd7e26e2299a71a466221ae638c641
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e1fed2591117fcee9f9508f0f261ba8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-99001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate |
2007-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97daf2a0d07024fd2246f8fb98694b86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b3ee19d512a7870d90ef66b2786e03c |
| publicationDate |
2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007135194-A2 |
| titleOfInvention |
Preparation and uses of gene sequences encoding chimerical glycosyltransferases with optimized glycosylation activity |
| abstract |
The present invention relates to the production of gene sequences encoding chimerical membrane glycosyltransferases presenting an optimized glycosylat ion activity in cells transformed with said sequences, said gene sequences corresponding to the fusion : of a first nucleic acid coding for a C-terminal minimal fragment of the catalytic domain (CD) of the native full length glycosyltransferase, to a second nucleic acid coding for a transmembrane peptide comprising in its N-terminal region a cytoplasmic tail (CT) region located upstream fro m a transmembrane domain (TMD), itself located upstream of a stem region (SR), provided that at least one of these CT, TMD, SR peptides being different from the primary structure of the naturally occurring peptide counterparts present in the native glycosyltransferase from which is derived the CD fragment with optimal glycosyltransferase activity as defined above. The invention also relates to the use of said gene sequences in the frame of the preparation of recombinant proteins of interest by cells transformed with said sequences and sequences encoding said recombinant proteins. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9809835-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2824176-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2821482-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9481902-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-422316-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421985-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015001034-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015003811-A1 |
| priorityDate |
2006-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |