Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28a89f8dab024e02ae765d1273e716f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d6df9f035b8fe9edb82b4120001eabf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_206463d498896f43533a655743f024c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_751757c5f3c7ee1744e7be3f9c57e9db |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
filingDate |
2007-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39e2e5a36dba9e2026fca7d116a58d2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27364410a332f1643e47a43b4ef73be9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19d238155307199f148a6d9232e6c68c |
publicationDate |
2007-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007132211-A1 |
titleOfInvention |
Acoustic wave transducer substrate and measurements using the same |
abstract |
An acoustic wave transducer substrate is provided, the substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites. The growth-promotion sites are preferably for promoting fibril formation. The invention also provides a method of screening a candidate compound for an effect on fibril growth, including the steps of: providing an acoustic wave transducer substrate having a surface with a plurality of growth promotion sites for promoting the accumulation of polypeptide molecules at said sites; causing oscillation of the substrate; contacting the substrate surface with a sample fluid comprising polypeptide molecules and a candidate compound; and measuring one or more parameters of the substrate oscillation to monitor the accumulation of said polypeptide molecules of interest in the presence and absence of said candidate compound. Alteration of the accumulation of said polypeptide molecules of interest in the presence of said candidate compound as compared with that in the absence of said candidate compound indicates that the candidate compound has an effect of fibril growth. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11771846-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11311686-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9375690-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9410873-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9751057-B2 |
priorityDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |