| abstract |
Compounds of formula (I) are inhibitors of PI3 kinase activity, and useful in treatment of, inter alia, autoimmune, inflammatory and proliferative diseases; wherein s is 0 or 1; U is hydrogen or halogen; X is -(C=O)-, or an optionally substituted divalent phenylene, pyridinylene, pyrimidinylene, or pyrazinylene radical, or a bond; P is optionally substituted C1-C6 alkyl and Z is -(CH2)Z-Y1-L1-R or Z is optionally substituted C1-C6 alkyl and P is -(CH2)Z-Y1-L1-R; and z, Y1, L1 and R are as defined in the claims. |