http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007127809-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8997d30ef988d43885f716f01df7500 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 |
| filingDate | 2007-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afa63d6156143fee89ecbcfe252d8ba6 |
| publicationDate | 2008-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2007127809-A3 |
| titleOfInvention | P8 modulation to control hypertension |
| abstract | The instant invention features several methods for treating hypertension. One such method features treating hypertension by a method including the step of administering to a patient, or a subject in need of such a treatment, an agonist, or an antagonist, of internalization of AT1 receptor after the AT1 receptor has bound angiotensin II. The instant invention also features a method for modulating the activity of an AT1 receptor by contacting the AT1 receptor with p8, a fragment of p8, or a functional derivative of p8. In particular embodiments, the AT1 receptor is contacted by a compound that modulates the interaction between the AT1 receptor and p8. In other particular embodiments, the contact between the AT1 receptor with p8, a fragment of p8, or a functional derivative of p8 occurs intracellularly. |
| priorityDate | 2006-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.