abstract |
Described herein are methods and compositions that can be used to prevent diabetes mellitus, or prevent or delay loss of residual -cell mass, providing a longer remission period and delaying the onset of diabetes related, usually progressive, complications at a later stage of the life. In addition, the methods described herein can be used to predict whether a subject, e.g., a subject with ongoing anti-insulin autoimmunity, will progress to T1DM, and to evaluate a subject's response to a therapeutic intervention. |