| abstract |
A compound having the formula: (I), (II), (III), or (IV) wherein: R is an electron withdrawing or electron moiety; R5 and R10 may be the same or different and are a straight or branched 1-5 carbon or heteroatom chain substituted terminally by a cycloalkyl or aromatic ring, or other structural isomer or complex thereof; n is the position of substitution of R; Z is N-R10, O, S, S=O, CH2 or C=O; y is 1-5 and Q is Z or NH, with the proviso that, where Z is NH, N-CH3, S or O and Rn is H, R5 may not be CH3; as well as quaternary ammonium salts thereof and their use as pharmacological compositions and for methods of treatment. |