http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007120658-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8767e22a17a5547eb645916ee3defdd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11d05e40924c78e685d633fda269401b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5743 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2007-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d02c9d72d51dab7fccf6eae7e8cfd350 |
publicationDate | 2007-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2007120658-A1 |
titleOfInvention | Melanoma biomarker and methods of uses |
abstract | The present invention relates to the use of TROY, also called tumor necrosis factor receptor superfamily, member 19 (TNFRSF 19) also called toxicity and JNK inducer (TAJ), in diagnosis and therapy of non-epithelial cancers, such as melanoma. Accordingly, the invention provides in vitro and in vivo diagnostic and/or prognostic methods for cancers, other than epithelial cancers, preferably melanoma, comprising analyzing TROY expression in a biological sample from an individual or in an individual, wherein expression of TROY in non-epithelial cells, such as in melanocytes, in indicative the biological sample or the individual containing malignant cells, such as malignant melanoma cells. The invention also provides therapeutic use of TROY targeting molecules, such as TROY antibodies or TROY targeting RNA interfering agents for treatment of cancer wherein the cancer cells express TROY. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010011310-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115786504-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115786504-B |
priorityDate | 2006-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1405.