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filingDate 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd68e0b80e764387aeb81acb08e2e901
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publicationDate 2007-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2007119789-A1
titleOfInvention Agent for suppressing arteriosclerosis
abstract An agent for suppressing arteriosclerosis containing an extract of banaba leaf belonging to Lagerstroemia in the Lythraceae family as an active ingredient and having an antagonistic action against lectin-like oxidized low-density lipoprotein receptor (LOX-1), the agent for suppressing arteriosclerosis having a suppressing action of oxidized LDL uptake into a cell via a scavenger receptor other than LOX-1, a food composition containing the agent for suppressing arteriosclerosis and a pharmaceutical composition containing the agent for suppressing arteriosclerosis. The invention provides the agent for suppressing arteriosclerosis which inhibits the binding of oxidized LDL to LOX-1 expressed in a vascular endothelial cell, macrophage or the like, has the antagonistic action having a ability to suppress oxidized LDL uptake into the cell via LOX-1 and is highly safe and the food or pharmaceutical composition containing the same.
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