| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc9cd96bc6cd40f3cdeb5a0cd8a0c51a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ae321fda6f6a5f29094cb25b5ac98c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66293b4b73dd28cac5d56c58e2de165e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 |
| filingDate |
2007-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36012395244bc67a3963a02765d57126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c75cd56b3764ea9ab264ad80ec7c92a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d19f91f7d9a941d5d82506d230c1f6b0 |
| publicationDate |
2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007115968-A3 |
| titleOfInvention |
Process for the preparation of a glucokinase activator |
| abstract |
Provided is a process for the preparation of 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxocyclopentyl)-N-pyrazin-2-ylpropionamide of formula (I) and its isopropanol solvate as a glucokinase activator which increases insulin secretion in the treatment of, for example, type II diabetes. The key step in the process is the conversion of a compound of formula (II) into a compound of formula (III) where P is an alkyl or alkylidene group forming an acyclic or cyclic ketal protective group. |
| priorityDate |
2006-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |