| abstract |
The present invention relates to lipid compounds of the general formula (I): wherein - n=0-2, - R1 and R2 are the same or different and may be selected from a group of substituents consisting of a hydrogen atom, an alkyl group, a halogen atom, and an alkoxy group; -, X is COR3 or CH2OR4, wherein - R3 is selected from the group consisting of hydrogen, hydroxy, alkoxy, and amino, - wherein X further comprises carboxylic acid derivatives when R3 is hydroxy and - R4 is selected from the group consisting of hydrogen, alkyl or acyl, - Y is a C9 to C21 alkene with one or more double bonds with E or Z configuration; or any pharmaceutically acceptable complex, solvate or pro-drug thereof. The present invention also relates to pharmaceutical compositions comprising such lipid compounds, and to such lipid compounds for use as medicaments or for diagnostic purposes. |