| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c9051ebf4d8202ac6f45a8fa7ccb0ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb2ad86aedd495afe084d1be63df4821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f68e375381e77ca3588a7f2ce2cef73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3400ec5c8342e9850fd68ec9e2319e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82a1eb8da77deaeb07c58071b51626f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb141b396e502bfce986c491d722e401 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-067 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 |
| filingDate |
2006-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b36d708cebcf6aa79b33d59a603166b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34e3ac9c3033f47b0775972f5e101525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0851eeffb22fdbbb38815886f555fbc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_314cc57c830dc81c584b3c185292e72f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f28860938134f662e788af15c88ca8b1 |
| publicationDate |
2007-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007100358-A3 |
| titleOfInvention |
Convergent synthesis of proteins by kinetically controlled ligation |
| abstract |
The present invention concerns methods and compositions for synthesizing a polypeptide using kinetically controlled reactions involving fragments of the polypeptide for a fully convergent process. In more specific embodiments, a ligation involves reacting a first peptide having a protected cysteyl group at its N-terminal and a phenylthioester at its C-terminal with a second peptide having a cysteine residue at its N-termini and a thioester at its C-termini to form a ligation product. Subsequent reactions may involve deprotecting the cysteyl group of the resulting ligation product and/or converting the thioester into a thiophenylester. |
| priorityDate |
2005-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |