| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aff7c26a04a3cfd78ce46060c503c4e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbd436cd7f986d0697a8e7053ba55f8d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c24dd9690a57c8b4c79ae9902753b45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_300d2afe0a8d854655e1502ac84d3ac6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd424c3a5b5c85fe1911588b16147232 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-62 |
| filingDate |
2007-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8789b5a8252d647e4127bf661d00bdab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b8c83f7b4fc1805ade40001fab9c3af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_246f14ab9a8263c23a3c3a68393a4795
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae405bf741e310951b860e6762e3de0e |
| publicationDate |
2007-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007095276-A2 |
| titleOfInvention |
Method for deprotecting aryl or alkyl sulfonamides of primary or secondary amines |
| abstract |
The invention relates to a method for removing an alkyl sulfonyl or aryl sulfonyl protecting group from a primary or secondary amine by contacting an alkyl sulfonamide or an aryl sulfonamide with a Stage 0 or Stage I alkali metal - silica gel material in the presence of a solid proton source under conditions sufficient to form the corresponding amine. The invention also relates to a method for removing an alkyl sulfonyl or aryl sulfonyl protecting group from a primary or secondary amine by a) reacting an alkyl sulfonamide or an aryl sulfonamide with a Stage 0 or Stage I alkali metal - silica gel material, and b) subsequently reacting the reaction product from step a) with an electrophile or a proton source. Preferred Stage 0 or Stage I alkali metal - silica gel materials include Na, K2Na, and Na2K. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102009008144-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9249480-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2081682-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2081682-A4 |
| priorityDate |
2006-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |