Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0deb71976c4dcad29812aa3e43c8437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0983ecab52c7a91894f5a6fcf0525cbf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y502-01008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
filingDate |
2007-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffba2b58ec1d6c67609c93e6e30a05af |
publicationDate |
2007-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007093807-A2 |
titleOfInvention |
Apoptosis methods, genes and proteins |
abstract |
A W303a Saccharomyces cerevisiae yeast cell which contains a polynucleotide that encodes a functional Bax polypeptide under the control of a galactose- inducible promoter that is integrated at the LEU2 chromosomal locus. A kit of parts comprising the yeast cells and a yeast plasmid vector suitable for transforming a cDNA library into the yeast cells. Use of the yeast cell for screening a cDNA library for a polynucleotide that is or encodes an inhibitor of B ax-mediated apoptosis. Genes and polypeptides that inhibit Bax-mediated apoptosis and which were identified from a human hippocampus cDNA library screened in the yeast cells. A method of combating Bax-mediated apoptosis in a cell using an inhibitor of Bax-mediated apoptosis which was identified from a human hippocampus cDNA library screened in the yeast cells. A method of promoting Bax-mediated apoptosis in a cell using an inhibitor or antagonist of the anti-apoptotic polypeptides identified from a human hippocampus cDNA library screened in the yeast cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010009892-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11098082-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010138869-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010009892-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012178719-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9267122-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111499742-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2009273471-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2009273471-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9529001-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2515054-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10520499-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010015032-A1 |
priorityDate |
2006-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |