http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007090082-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faaa61c2d5eb6948656a5a19dc4e3a15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30f88fce90a96087c564b89062ebe51d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ed64e02bfb25eac62b65e450b8cd325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5a0c0281a3586f1acc39d411a503407 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
| filingDate | 2007-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0400924be124a2174a23b829edf50efb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e9a0f4c1c51f8fb850bcac0e0cda7c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0e8d85cc6b3a83672db155216933a30 |
| publicationDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2007090082-A3 |
| titleOfInvention | Drug delivery systems comprising weakly basic selective serotonin 5-ht3 blocking agent and organic acids |
| abstract | A pharmaceutical dosage form such as a capsule, a conventional or orally disintegrating tablet capable of delivering a weakly basic, nitrogen (N)-containing selective serotonin 5- HT3 blocking agent having a pKa in the range of from about 5 to 14 and a solubility of not more than about 200 µg/mL at pH 6.8 into the body in a sustained-released fashion, suitable for a once-daily dosing regimen, comprises at least one organic acid, which solubilizes said weakly basic selective serotonin 5-HT3 blocking agent prior to releasing it into the hostile intestinal environment wherein the blocking agent is practically insoluble. The unit dosage form may be composed of a multitude of multicoated particulates (i.e., immediate-release beads, sustained-release beads and/or one or more timed, pulsatile- release bead populations) and is designed in such a way that the weakly basic blocking agent and the organic acid do not come into close contact during processing and/or storage thereby avoiding in-situ formation of acid addition compounds while ensuring that the acid is not depleted prior to completion of the drug release. |
| priorityDate | 2006-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.