| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5f9acef6b726766886ddd412aede1ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c668ddc4274cd4e25c48d8b938c466a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5188a6bfc071da868a2600333e9626b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97f2578a1b7ae23ef9694633d08e476f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1289
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-35 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40 |
| filingDate |
2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c02f827d470e78ccc53f406b371228d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f866a63730743f20833ad1ae047d65c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3a5080a243d6d7f948555779fe2bc8f |
| publicationDate |
2007-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007087679-A1 |
| titleOfInvention |
Methods of diagnosis and treatment of m. tuberculosis infection and reagents therefor v |
| abstract |
The present invention provides isolated M. tuberculosis ribosomal protein S9 (SEQ ID NO: 1) and immunogenic peptide fragments thereof (any one of SEQ ID NOs: 2-7), and antibodies produced against the full-length protein and immunogenic peptide fragments for the diagnosis of M. tuberculosis infection in humans, for example using an antigen-based sandwich ELISA format. The present invention also provides multi-analyte assays in which the S9-based diagnostic assays of the present invention are multiplexed with the detection of immunogenic epitopes from other proteins from M. tuberculosis e.g., epitopes of the BSX protein (any one of SEQ ID NOs: 8-18) and/or glutamine synthetase protein (any one of SEQ ID NOs: 19-22) and/or the detection of antibodies against one or more other M. tuberculosis proteins in humans, uincluding antibodies against BSX and/or glutamine synthetase. |
| priorityDate |
2006-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |