| abstract |
Systems comprising lectin-based arrays and mass spectrometry means and their use in the identification and detection of aberrant glycoproteins in cancer and cancer diagnosis are provided. The lectins of the arrays comprise members collectively cognate to galactosamine, N-acetyl-galactosamine, N-acetyl neuraminic acid, mannose, and O-glycosidically linked oligosaccharide (e.g., an array comprising PNA, ECL, and Jacalin) Glycoprotein biomarkers of cancer identified by use of the methods are also provided. |