| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa312244175fc5acbf0c129dfdbbee97
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b04b07294180189ec67ae3f2d1a32588
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5395851992b7442f8ddfb118afef39a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca10e34ed379358f5c43c04ab6b889a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_150846022f9e7f3a38831ad9d97f165e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-6615 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N65-00 |
| filingDate |
2006-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_793ad03d6d58c505f2d33a48fd747ed1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18854f93c68398a1688427ceeca3d3fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef7e1f7e4bf503371e45f24fbe08cccf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45d38864969abe519d38fcc90c478c4c |
| publicationDate |
2007-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007081315-A1 |
| titleOfInvention |
Use of inositol-tripyrophosphate in treating tumors and diseases |
| abstract |
Inositol-tripyrophosphate is an allosteric effector of hemoglobin due to its ability to cross the plasma membrane of red blood cells and deliver oxygen to solid tumors, by lowering the oxygen affinity of the hemoglobin of red blood cells. The present invention is directed to the use of inositol-tripyrophosphate to reduce hemoglobin's affinity for oxygen in circulating red blood cells. The present invention is further directed to the use of inositol-tripyrophosphate to inhibit angiogenesis and enhance radiation sensitivity of hypoxic tumors. The present invention is further directed to the use of inositol-tripyrophosphate to enhance PO2 in hypoxic tumors. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2451459-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919481-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1863495-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8178514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1863495-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9078908-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2451459-A4 |
| priorityDate |
2006-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |