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filingDate 2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_648baee65295cba934672c75a89cbfb9
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publicationDate 2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2007073596-A1
titleOfInvention Degradable polymeric microsphere composition
abstract The present invention is directed towards a biodegradable microsphere composition for prolonged controlled release delivery of at least one biologically active agent in vivo. The instant invention provides microspheres prepared from amphiphilic block, star shape or graft copolymers made of poly(N-vinyl-2-pyrrolidone) segment(s) and biodegradable segment(s), the microspheres incorporating at least one biologically active agent and being adapted for controlled delivery of the active agent to a mammal. Poorly water-soluble biologically active agents are incorporated into the microspheres by a single emulsion method. Hydrophilic biologically active agents are incorporated into the microspheres by a double emulsion method. Amphiphilic biologically active agents are incorporated into the microspheres by either a single or double emulsion method.
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priorityDate 2005-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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