Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cc7598de4ef61941664eedaca3ca04e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b53b5ea8e978d94f28885ddbb1b798 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09e7e9b3d84ccde25c086c58c8f1bed2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7bfdac5e9641ec5260cd605d227ad3a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-98 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 |
filingDate |
2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fded073ba530b57655e6db69eaa5326 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a43bcadf2a691a6f3872e6f401058151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4bc640b6cdb2e9734d0112a849ba0d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3205cd2be306bdd9c8774ec387d2fa50 |
publicationDate |
2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007067732-A3 |
titleOfInvention |
A scintillation proximity assay for identifying inhibitors of fatty acid amide hydrolase |
abstract |
Assays for screening compounds suspected of binding fatty acid amide hydrolase (FAAH) using scintillation proximity assay (SPA) technology are described. The assays utilize the interactions of reversible inhibitors such as [3H]-R(+)-methanandamide (MAEA) and membrane-associated FAAH5 such as FAAH- containing microsomes, to evaluate the displacement activity of candidate FAAH inhibitors. The assays are specific for FAAH where FAAH binding compounds can be detected. Various embodiments of the assay have been validated and demonstrated to be simple, sensitive and amenable to high-throughput screening. Kits for performing the assays are also disclosed. |
priorityDate |
2005-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |