Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_269b0b2f24ff2790756289fa3ac1b9fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b4ad1fdc367301298e3639deeb608e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b51c72391666bb0b5fa29a97bb72fa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0eb9f0c030db025eaa8e8e4fe23341f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebb8b1fb05e13f5e7922e38935bf2e9b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
filingDate |
2006-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_035130aaa0a29d2fb3e5ce1ce502fd74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b219651564f7b3bcdf60e8fecde37136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_336906886bbf0151b54881ad4f722cf6 |
publicationDate |
2007-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007066069-A3 |
titleOfInvention |
Process for the preparation of poly(alkoxylated) oligonucleotides |
abstract |
A process for the preparation of a poly(alkoxylated) oligonucleotide is provided. The process comprises reacting an oligonucleotide which has been purified by ultrafiltration with a poly(alkoxide) thereby to form a poly(alkoxylated) oligonucleotide. The poly(alkoxyalted) oligonucleotide may be separated from non-poly(alkoxyalted) oligonucleotide by ultrafiltration under denaturing conditions, such as the presence of organic solvents, for example, ethanol; the presence of urea; the addition of chaotropic salts, for example perchlorate and guanidinium salts; the presence of formamide; and the application of heat, for example a temperature of up to about 70°C. |
priorityDate |
2005-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |