| abstract |
The invention provides a cationic polymer which is nearer to components of the human body and capable of forming a polyion complex together with an anionic component such as hyaluronic acid, more specifically, a cationized hyaluronic acid, namely, a hyaluronic acid characterized in that at least part of the hydroxylic hydrogen atoms are replaced by groups having quaternary ammonium cations. The cationized hyaluronic acid can be synthesized by reacting hyaluronic acid with a cationizing agent such as glycidyltrialkylammonium halide or the like. The cationized hyaluronic acid together with hyaluronic acid can form a polyion complex gel in the coexistence of water. |