| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0a5da74eacd4a1d13f593b7c9f1009d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45a3703d03a4b21be619937f5ad63b8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7576a3be671a1623338950d45ca3d1bb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4995
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-498
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 |
| filingDate |
2006-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fe4c2b0dbe1cda66bc9f85e6a56389a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2b9ffb1eb12a5e76136e18fb8f44380 |
| publicationDate |
2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007062413-A2 |
| titleOfInvention |
Use of parp-1 inhibitors |
| abstract |
A method for improving the cytotoxic effect of Ecteinascidin-743 (ET-743) or an analog thereof on a tumor cell population in a patient the method including administering to the patient, sequentially or simultaneously, a therapeutically effective combination of a composition including ET-743 and an amount of a composition including a PARP-I inhibitor effective to increase the cytotoxic effect of ET-743 on the tumor cell population. Anti-tumor compositions containing a therapeutically effective amount of ET-743 and an amount of a PARP-I inhibitor effective to increase the tumor cytotoxicity of the ET-743 are also presented. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010284964-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8729080-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014102817-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012014221-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108368059-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022043245-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3960177-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9486449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9359367-B2 |
| priorityDate |
2005-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |