| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ac96eeece7537dbed1f4e66ab855fe2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dedc8e60e323a58ca2a7275d62d5b587
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d595e9ec57ddc76a7dadba474ceeb17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3a6ab30195ce814242a842cd415d3bc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 |
| filingDate |
2006-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_596c1b9ece9112ae1068413b550e12b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d63c894fdc97195b9b7396e36a36be9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc4c6512ffc3f26532a20b93bd2cd957 |
| publicationDate |
2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007059605-A1 |
| titleOfInvention |
Composition and method for efficient delivery of nucleic acids to cells using chitosan |
| abstract |
There is disclosed a composition and a method for the efficient non-viral delivery of nucleic acids to cells using chitosan. In order to achieve high efficiency of transfection, the composition contains a nucleic acid and a chitosan that has the following physico-chemical properties: a combination of a number-average molecular weight between 8 kDa and 185 kDa and a degree of deacetylation between 72% and 92%. The chitosan molecule can also present additional physiochemical properties such as a block distribution of acetyl groups obtained by a heterogeneous treatment of chitin, and/or a polydispersity index between 1.4 and 7.0. By correctly controlling these parameters, efficient delivery systems may be produced that are effective when optimized for different conditions such as the pH of transfection media and amine-to-phosphate ratio. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7875449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013157967-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2034954-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846102-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10383971-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9404088-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012159215-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9642871-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10765698-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2034954-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014197970-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012040004-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008031899-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014518875-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9809821-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10206938-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011140638-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10561677-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008031899-A2 |
| priorityDate |
2005-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |