| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c114352a0793cf71b1859df5322c678
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d31c60c39a5860edd950d31f2af8ccb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93dc6c9f11a58da639ed0c6aa7922cd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70765042c559d5875430770edb0372d3 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-655 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 |
| filingDate |
2006-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6ae3b8e961f95f6b2c7f77c9c2339d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8f405d4036d8a733c39b9ab5d212cf3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_583b158e8d0e26da37fdac0a923f985f |
| publicationDate |
2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007056214-A3 |
| titleOfInvention |
N-alkyl-n-aryl-thienopyrimidin-r-amines and uses thereof |
| abstract |
Disclosed are N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs thereof, represented by the Formulae I-II: wherein Ar, R1 -R4 and R10 are defined herein. The present invention relates to the discovery that compounds having Formulae I- II are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs. |
| priorityDate |
2005-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |