| abstract |
The present invention relates to a tricyclic compound of formula (I): (I) (where R 1, R 2, R 2 ', R 3, R 4, X, Y and Z are as defined in the description) and a pharmaceutical product containing said compound. The compound according to the invention has an inhibitory action with respect to the synthesis of squalene as well as an inhibitory action vis-à-vis the synthesis of cholesterol. It can therefore be used as a pharmaceutical, for example as a prophylactic and / or therapeutic agent for hyperlipidemia such as hypercholesterolemia, hypertriglyceridemia or high density hypolipoproteinemia and / or arteriosclerosis for the treatment of mammals , including humans. |