http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007054977-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_821d85fa66fb9a70cc8f3306cc129b1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5262e68005339a2cd40c628d0284beeb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H5-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-10 |
filingDate | 2006-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e273b547ccc515c3f7dbee50e0d2fef7 |
publicationDate | 2007-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2007054977-A2 |
titleOfInvention | Method and composition for skin depigmentation |
abstract | The present invention relates to a compound of formula I: [(C)-(L')]n-(A)-[(L)-(B)]m wherein (A) is a thioglycosylated cysteine of formula IIa or IIb: IIa IIb; (B) is a melanogenosis-inhibiting peptide comprising peptide sequence selected from a group consisting of: (i). Glu-Asp-Tyr-His-Ser-Leu-Tyr-Gln-Ser-His-Leu; (ii). Ser-Gly-Gly-Tyr-Leu-Pro-Pro-Leu; and (iii). His-Ser-C(O)-NH-(CH2)k-CH2-C(O)-NH-Ser-His; (C) is a tyrosinase inhibitor; n is 0 or 1; m is 0 or 1; m + n is 1 or 2;k is 2-10; X1 is O or NH; R1, R2, R7, and R8 are each, independently, selected from H, and a bond in a linkage group between (A) and (L); R3, R4, R5, R6, R9, R10, R11, and R12 are each, independently, selected from H, a saccharide, and a bond in a linkage group between (A) and (L'); (L) is a linker which forms linkage groups with thioglycosylated cysteine (A) and melanogenosis-inhibiting peptide (B); and (L') is a linker which forms linkage groups with thioglycosylated cysteine (A) and tyrosinase inhibitor (C). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9883998-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9168398-B2 |
priorityDate | 2005-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 372.