Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57fe035bf51796b1b32acf47034c800c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b3db7dd56b56cc6d94d0e0cccc38322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fff933bfcdf23b78231905bfea278da |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-743 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
filingDate |
2006-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5ccda835f1688c301ac3b9b5d25cea1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b1fadf0a70f07901b36657e299367c3 |
publicationDate |
2007-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007054791-A2 |
titleOfInvention |
Androgen glucuronides as markers of androgenic activity |
abstract |
Embodiments of the invention provide methods for diagnosis of diseases and disorders related to androgen amount. This is accomplished by detecting androgen glucuronide derivatives, such as androsterone (ADT) and/or androstane-3α , 17β -diol (3α -diol) in blood or tissue. In some embodiments of the invention glucuronide derivatives (or their absence) are detected by mass spectrometry (LC-MS/MS) and/or gas chromatography - tandem mass spectrometry (GC-MS). A low amount of glucuronide derivatives in relation to the mean amount of glucuronide derivatives in a comparable sample population is indicative of androgen deficiency. Further embodiments provide methods for treating skin that exhibits signs of ageing, as well as methods for testing the efficacy of compositions for treating skin that exhibits signs of ageing. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008054214-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8227453-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10314848-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10441592-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8669242-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8653051-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9700566-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9333203-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8648060-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8575139-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211334-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008054214-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9597335-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9192669-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9737548-B2 |
priorityDate |
2005-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |