http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007051520-A2

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filingDate 2006-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2007051520-A2
titleOfInvention Method and device for producing very fine particles and coating such particles
abstract Disclosed are methods and devices for producing very fine particles which are then coated with protective polymers in another step of the process. The particles are produced using a method in which a liquid flow comprising a particle-free liquid 1 that contains the active substance in a dissolved form is combined with a second liquid flow comprising a liquid 2 in a high-energy zone or no sooner than two seconds before reaching the high-energy zone. Said two liquids can be mixed with each other while the active substance dissolved in liquid 1 is insoluble or more difficult to dissolve in liquid 2 than in liquid 1 and settles in the form of particles in the high-energy zone or within a maximum of 2 seconds before reaching the high-energy zone when the two liquids are mixed. The obtained particles are introduced into an aqueous outer phase which contains the coating materials in a dissolved form and are then subjected to a drying step such that said materials settle on the particles as a closed coating. The coated particles are protected from damaging influences and are provided with modified release kinetics compared to uncoated particles.
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priorityDate 2005-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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