| abstract |
A novel solid oral dosage forms comprising valsartan and hydrochlorothiazide (HCTZ) and a process of forming the same. The novel solid oral dosage form comprises a core comprising an effective amount of valsartan or a pharmaceutically acceptable salt thereof, and pharmaceutically acceptable additives suitable of the preparation of solid oral dosage form; and an outer coating comprising an effective amount of hydrochlorothiazide (HCTZ). The process of preparation of the novel solid oral dosage form of valsartan, comprises blending valsartan with the pharmaceutically acceptable excipients, dry granulation, milling and screening to obtain granules, said granules being subsequently compressed to tablets and coated, wherein hydrochlorothiazide is added in the coating dispersion. |