Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a4f8fd5e780830cc199259d0c64b6ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a70b05f3bdf7f6e9aaf7a41ac3aacdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05fca5a29c358c9f1a44049e734bd132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e8aad5afd836a171df2a624e38a40ae |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 |
filingDate |
2006-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6f80276b03fe46e39fb948241794f70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02b6fee8c0ee1e6d163d52e46884ab54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3560695f3a521405e809465224d23dbc |
publicationDate |
2007-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007047998-A2 |
titleOfInvention |
Mutations and polymorphisms of hdac2 |
abstract |
This invention relates generally to the analytical testing of tissue samples in vitro, and more particularly to aspects of genetic polymorphisms and mutations of the HDAC2 gene. The invention provides new HDAC2 mutations and SNPs, useful in the diagnosis and treatment of subjects in need thereof. Accordingly, the various aspects of the present invention relate to polynucleotides encoding the HDAC2 mutations of the invention, expression vectors encoding the HDAC2 mutant polypeptides of the invention and organisms that express the HDAC2 mutant and polymorphic polynucleotides and/or HDAC2 mutant/polymorphic polypeptides of the invention. The various aspects of the present invention further relate to diagnostic/theranostic methods and kits that use the HDAC2 mutations and polymorphisms of the invention to identify individuals predisposed to disease or to classify individuals with regard to drug responsiveness, side effects, or optimal drug dose. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019014418-A1 |
priorityDate |
2005-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |