| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77c2f907d13534169a46ac8441351f38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2a0c5628ed9f6f93dd3f29f11297fcf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a8dbccb40a707aefb845b25ae7a5ee6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_646acd82cfe6e936cb3079d5ea0a6c22 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-827 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B30-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6903
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 |
| filingDate |
2006-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5204537cd289f6f4bedbc5b536466032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4b1f444d0b98bc3b4d1d12c296b84bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_229acd540bfe66661b86ad330850812a |
| publicationDate |
2007-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007047922-A2 |
| titleOfInvention |
Polymer-drug conjugates |
| abstract |
A conjugate that includes a drag covalently linked to a polymer. Upon administration, the conjugate is digested by an enzyme that is present at the site of administration thereby releasing a therapeutic agent. The conjugate may demonstrate substantially the same pharmacokinetic and pharmacodynamic behavior as the drug itself. A material for controllably releasing a conjugate in response to the local concentration of a molecular indicator. The material includes a plurality of conjugates and a plurality of multivalent cross-linking agents. The polymers of the conjugates include an analog of the indicator within their covalent structure. The multivalent cross-linking agents include cross-link receptors that interact with the indicator analog and thereby cross-link the conjugates. These non-covalent interactions are competitively disrupted when an amount of the molecular indicator is present thereby causing the material to release the conjugate in a manner that is dependent on the local concentration of indicator. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8981050-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9771406-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9758561-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9751926-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9789165-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9775904-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107750168-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10253079-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016193371-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10300144-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10806797-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9889205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932381-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9884125-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009083561-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982029-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9387456-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8840923-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8394921-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9228010-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014170713-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2719482-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188739-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2408808-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10758592-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9492556-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010107519-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012184631-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9670261-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9694053-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008012528-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11642415-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012520879-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9908934-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9427475-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9789163-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9750788-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9745360-B2 |
| priorityDate |
2005-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |