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filingDate 2006-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70033620491c96aa4b692dce36f2e8e9
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publicationDate 2007-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2007042494-A2
titleOfInvention Microbiological production of 3-hydroxypropionic acid
abstract The invention relates to a cell which is genetically modified in relation to a wild type and exhibits at least one following properties: a) the activity of an enzyme E<SUB>1</SUB>, which is used for catalysing the conversion of pyruvate into oxalacetate or of an enzyme E<SUB>1b </SUB>for catalysing the conversion of phosphoenolpyruvate into oxalacetate, and which is greater than the wild type activity and b) the activity of an enzyme E<SUB>2</SUB>, which is used for catalysing the conversion of aspartate into beta-alanine and which is greater than the wild type activity, wherein the inventive cell, in addition to the a) and b) properties, is characterised in that it exhibits at least one following property: c) the genetically modified cell is capable to eject beta-alanine therefrom and d) the genetically modified cell is capable to convert the beta-alanine into the 3-hydrixypropionic acid. A method for producing a genetically modified cell, the genetically modified cells obtainable by said method, a method for producing the 3-hydrixypropionic acid, a method for producing an acrylic acid, a method for producing polyacrylates, a method for producing acrylic acid esters and the use of cells for producing the 3-hydrixypropionic acid are also disclosed.
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