| abstract |
The present invention is concerned with substituted imidazo[1,5-a][1,2,4]triazolo[1,5- d][1,4]benzodiazepine derivatives of the following formula (I) wherein the definition of substituents is described in the claims. It has been found that this class of compounds show high affinity and selectivity for GABA α5 receptor binding sites and might be useful as cognitive enhancer or for the treatment of cognitive disorders like Alzheimer's disease. |