Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52f61833386af7e60844c8f30754ed95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36ebe47bc71ea68de438bdce76bb10ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b52997d3a2cc05e0e97b143c74657bc6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-025 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12H1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12G3-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12H1-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-43 |
filingDate |
2006-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0de7e4830bb7631ba9b860da5e0b0514 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db2cdb7aad825e94bc07fba41eefbf70 |
publicationDate |
2007-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007036233-A2 |
titleOfInvention |
Dekkera/brettanomyces cytosine deaminases and their use |
abstract |
The present invention relates to cytosine deaminase protein and cDNA from various species of the yeast genus Dekkera/Brettanomyces. Compared to yeast cytosine deaminase the novel cytosine deaminases are more efficient and have a higher stability. The invention also relates to the field of suicide gene therapy based on activation of a non-toxic prodrug, 5- fluorocytosine to a toxic drug 5-fluorouracil based on the enzymatic activity of novel cytosine deaminses. Finally the invention provides use of 5-fluorocytosine for controlling the growth of Dekkera/Brettanomyces yeast. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108414596-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11344608-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11517631-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11015210-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10842885-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108414596-B |
priorityDate |
2005-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |