| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad3d385934289923d0200f87d6be5eb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f99dff01b87ed25d5487fc4bd6816e6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0eac3f014d16df2a9f4004e21878b546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1bf612b3df8713bf5a489cbf9255c98 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5067 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2005-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07e314081e5c80a91c581646362047d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_353ed9a52ecac52759c95a0b4ea4f10e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65b6e9e479effc588f3a0d4f9fff42ea |
| publicationDate |
2007-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007035082-A1 |
| titleOfInvention |
Immortalized fetal liver cell lines |
| abstract |
The present invention relates to a human fetal hepatocyte cell line that is derived from primary human fetal hepatocytes. The hepatocyte cell line is cloned and is immortalized by increasing telomerase activity in the cell. The hepatocyte cell line is capable of producing urea, as well as capable of elimination of ammonia, lidocaine and/or galactose and the cell line has the ability to differentiate into functional mature hepatocytes. The invention further relates to methods for generating such human fetal hepatocyte cell lines and to methods in which the- cell lines are used for the production, bioconversion and/or removal of substances from body fluids such as blood in e.g. bio-artificial liver systems. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011067671-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011136101-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016140336-A |
| priorityDate |
2005-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |