Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dd316fad501df2036e6c127743cb339 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79eea6a0556927cd25d1bcb556b81d1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44a52b34798c5451bfbb2ca1d11b096f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a933a0dd561e3e50b278738704d5c6e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b19c7f616757b04ac25868815485fc |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
2006-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b5d44c3e9cf520496fdc221c5fbf141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdf9ea575ab321008df6ccd305be9cee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d84378815b818e455d47eb9ead6fed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b50eef0d2c0d82d9801879de4846a851 |
publicationDate |
2007-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007033298-A3 |
titleOfInvention |
Hydrolase and methods for its use |
abstract |
This disclosure provides methods for catalyzing the release of ADP-ribose from poly(ADP-ribose) or O-acetyl-ADP-ribose. Also provided are methods for modifying DNA repair or chromatin structure by introducing into the cell an agent that modifies the activity of an ARH3 polypeptide, or variant or fragment thereof. Further provided are methods for screening molecules involved in the poly(ADP-ribosyl)ation of proteins or O-acetyl-ADP-ribose content, and method for treating disorders by altering activity of an ARH3 protein. |
priorityDate |
2005-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |