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filingDate 2006-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2007032376-A1
titleOfInvention SECRETORY IgA AND IgG ANTIBODIES-INDUCING AGENT
abstract It is intended to provide a nasal vaccine capable of inducing the production of secretory IgA and IgG antibodies which are specific to a Flavivirus such as a Hantavirus. It is also intended to provide a method of preventing infection with a Flavivirus by inducing the secretory IgA and IgG antibodies as described above. Namely, a nasal vaccine whereby favorable secretion of IgA antibody on the nasal mucosa and an IgG antibody response in the serum can be established, characterized in that a vaccine comprising an inactivated antigen originating in a Flavivirus and Poly(I:C) or a ceramic-processed surf clam powder employed as an adjuvant is nasally administered; and a method of inducing IgA and IgG antibodies specific to a Flavivirus characterized by comprising administering an inactivated antigen of a Flavivirus and Poly(I:C) or a ceramic-processed surf clam powder employed as an adjuvant to the mucosa of an respiratory organ.
priorityDate 2005-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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