http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007020960-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-00
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filingDate 2006-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f609fd158a453dd3d54325940fac142
publicationDate 2007-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2007020960-A1
titleOfInvention Process for producing carbapenem derivatives through reactions without isolating intermediates
abstract An industrially advantageous process for the production of carbapenem derivatives, namely, a process for the production of compounds (V), solvates thereof, or crystals of the solvates, characterized by comprising the first step of reacting a compound (I) with a metal catalyst in a solvent to form a compound (II), the second step of mixing the compound (II) containing reaction fluid obtained in the first step with diphenylphosphochloridate and a base to form a compound (III), and the third step of mixing the compound (III) containing reaction fluid obtained in the second step with a compound (IV) or a salt thereof to form a compound (V): wherein R1 is a carboxyl-protecting group; R2 is hydrogen or a hydroxyl-protecting group; and R3 is hydrogen or an amino -protecting group, with the proviso that neither compound (II) nor compound (III) is isolated.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101613351-B
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Total number of triples: 26.