| abstract |
Compounds according to formula (I) wherein the radicals R1, R2 and R3 are as herein defined, and wherein Ar represents an aryl group or heteroaryl group, preferably phenyl, n is 1 or 2, and the radical X represents a group selected from -C(Ra)(Rb)-, -C(Ra)(Rb)-C(Ra)(Rb)-, -C(Ra)=C(Ra)-, OC(Ra)(Rb)- or SC(Ra)(Rb)- . These compounds and their pharmaceutical acceptable salts are used in pharmaceutical compositions as prostaglandine D2 receptor antagonists useful in the treatment of CRTH2 -mediated diseases such as respiratory, inflammatory or allergic conditions among others. |