| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c39fd8026c719c970650e5ce6b04fc08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba3b05dcaaa876d8a4e4700db8f765c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac662aa2bb5d09715dd53fd7cd490b9e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-175 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L1-305
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-28 |
| filingDate |
2006-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1b171a7b259b78bb83ac87c3c16f906
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e445cd4032cf5d63495419e7e5f293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_098b4b0b42aaabb644baad2a5be65c3a |
| publicationDate |
2007-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007019440-A3 |
| titleOfInvention |
Method for producing l-carnitine or acetyl-l- carnitine from germinating seeds |
| abstract |
Acetyl-L-carnitine (ALCAR) and L-carntine (LCAR) are nutraceuticals with indications in treating a variety of mental health disorders. A metabolomics- guided bioprocess method is presented to enhance ALCAR and LCAR formation in germinating plant seeds. Metabolic fluxes are manipulated by germination in bioreactors to increase oxygen availability as well as provide an aseptic environment to alter carbohydrate consumption and feedback repress gluconeogenesis. Large shifts in sunflower seed fatty acid, phospholipid and high-energy metabolism change the germination environment and these metabolic changes lead to an approximate 1000- fold increase in natural LCAR and ALCAR production by the seeds. The resulting LCAR and ALCAR products from the seeds are used for treating mental health disorders including Alzheimer's disease, geriatric depression, non-geriatric depression and schizophrenia. |
| priorityDate |
2005-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |