abstract |
The invention relates to a method of obtaining tryptamine derivatives (I), wherein R is a radical of a heterocycle, comprising the decarboxylation of the corresponding derivative of 3-(2-aminoethyl)-1H-indole carboxylic acid and the subsequent methylation of the amino group. Compounds (I) include zolmitriptan and rizatriptan which can be used for the treatment of migraines. |