abstract |
The invention relates to the compounds of formula (I), wherein R, X, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP> and R<SUP>4</SUP> are defined as in claim 1. The inventive compounds are tyrosinkinase, especially TIE-2, and Raf kinase inhibitors and can inter alia be used in the treatment of tumors. |