http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007013592-A1

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filingDate 2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae584771367f0d447a347e4bc7e067f
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publicationDate 2007-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2007013592-A1
titleOfInvention Novel method for synthesis of intermediate in synthesis of carbapenem using sugar template
abstract Disclosed is a method for producing an intermediate in the synthesis of a useful carbapenem anti-bacterial agent with good efficiency, more specifically the method described above which enables the introduction of a methyl group into position 1 of the carbapenem skeleton in a highly stereoselective manner and does not need the use of any expensive asymmetric auxiliary group, any catalyst that may cause an ultra-low temperature reaction or have any toxicity to a human body or the like and can recover the auxiliary group. In this method, a sugar template containing a propionate unit represented by the formula (II) is reacted with an acetoxyazetidinone represented by the formula (III) to form a carbon-carbon bond between them, thereby introducing a methyl group into position 1 of the carbapenem skeleton in the desired β-stereoselective manner.
priorityDate 2005-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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