Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ab1003b3a3cf28326f9bb6b509d2d08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5469c60e6f6c82d8ee2c5ddb520ce74d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7dfd84f9157ae12c41e319ec325338d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f742a4af92b2cdfe87561c446ef78976 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd19ba8e1b6b2ce413bab653503beb02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8aec0cb6dc59b3891278c098fb89beb5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-02 |
filingDate |
2006-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae584771367f0d447a347e4bc7e067f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9382ef9bc3c2736d7dee2c9839a17110 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5510f4db625a72c0280a0ea39457af1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afe999fea733fe14696f73dbdc4d2509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c50067203aadfa278adf688cf897194 |
publicationDate |
2007-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007013592-A1 |
titleOfInvention |
Novel method for synthesis of intermediate in synthesis of carbapenem using sugar template |
abstract |
Disclosed is a method for producing an intermediate in the synthesis of a useful carbapenem anti-bacterial agent with good efficiency, more specifically the method described above which enables the introduction of a methyl group into position 1 of the carbapenem skeleton in a highly stereoselective manner and does not need the use of any expensive asymmetric auxiliary group, any catalyst that may cause an ultra-low temperature reaction or have any toxicity to a human body or the like and can recover the auxiliary group. In this method, a sugar template containing a propionate unit represented by the formula (II) is reacted with an acetoxyazetidinone represented by the formula (III) to form a carbon-carbon bond between them, thereby introducing a methyl group into position 1 of the carbapenem skeleton in the desired β-stereoselective manner. |
priorityDate |
2005-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |