http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007009303-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ac2ca0278ddc0c1d5b0723dbd8b1b7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_323be22d6285b554ea14b2b19bc4e633 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-067 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-067 |
filingDate | 2005-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fad114dc12aaa0489588d2ac31c3b308 |
publicationDate | 2007-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2007009303-A1 |
titleOfInvention | Process for synthesizing n4-acyl-5'-deoxy-5-fluorocytidine derivatives |
abstract | The present invention discloses a process for synthesizing Compound (I) of N4-acyl-5'-deoxy-5-fluorocytidine derivatives. The present invention utilizes Bis (trichloromethyl) carbobate as acylating agent for introducing protective lactone ring to the hydroxyl of saccharide moiety, and uses 5'-deoxy-5-fluorocytidine (Compound II) as starting material through key intermediate of Compound (III) and Compound (IV) to obtain target compounds through 3 steps. The process of the present invention has certain advantages such as high yield, short work-up time, available starting material, and convenience for industrial manufacture on a large scale. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011067588-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011104540-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109651451-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109651451-A |
priorityDate | 2005-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.