http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007008146-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6978e6d1bbd089f55f5a1ed78f7752d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ace27b7ac38a049073b1578409e18953 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f64cd8dac9e6760f8e506fb0a06b7a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48e67bcdf9d941d3b60b06b367202073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c7ab80e1231e3d7e197dfa681fe345b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_082a49577f1a9e39700671b98302fa01 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 2006-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9446e829690a1e184f8872b7a5253ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30e0688a48092aeec729002fd79d0d59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f4f98b7b8d71686dc24c8299b5c266d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c83d70ede2a3b248f9412eeece47a77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf4faeb6fb02ee32d0f5dada933dcb2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaa74718de3ee2cf9ff9e0b740bc2f54 |
| publicationDate | 2007-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2007008146-A1 |
| titleOfInvention | Heterocyclic sulfonamide derivatives as inhibitors of factor xa |
| abstract | The invention relates to compounds of formula (I), Chemical formula should be inserted here. Please see paper copy wherein R1, R2, R3 and R4 are independently selected from carbon and nitrogen, and where at least one of R1, R2, R3 and R4 is nitrogen; A1 is a single bond or a double bond; n is 0, 1, 2 or 3; each R5 is independently selected from hydrogen, halogen, C1-3 alkyl, oxo, oxy, oxido and thioxo; R6 is hydrogen or oxo; m is 0, 1, 2 or 3; A2 is a single bond or a double bond; each R7 is independently selected from hydrogen, hydroxy, oxo, C1-5alkyl, carboxy, cyano, tetrazolyl, N-C1-5alkyltetrazolyl, oxazolyl, C1-5oxazolyl, isoxazolyl, C1-5isoxazolyl, hydroxyC1-5alkyl, carboxy C1-5alkyl, C1-5alkoxyoxo C1-5alkyl, carbamoyl, C1-5alkylcarbamoyl, di(C1-5alkyl)carbamoyl, carbamoyl C1-4alkyl, C1-5alkylcarbamoyl C1-4alkyl, di(C1-5alkyl)carbamoyl C1-4alkyl, hydroxy C1-5alkylcarbamoyl, C1-5alkoxy C1-5alkylcarbamoyl, hydroxy C1-5alkylcarbamoyl C1-4alkyl, C1-5alkoxy C1-5alkylcarbamoyl C1-4alkyl, -CONR8(CH2)xS(O)pR9, -CONH(CH2)qNR10R11, -C1-5alkyl-Y1, -COOCHR17R18 and -CON R17 R18; and R30 is hydrogen, amino, methyl or halogen; or a pharmaceutically acceptable salt thereof, said compounds possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the compounds, to their use, to pharmaceutical compositions comprising them, to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect, and to combinations comprising them. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3078378-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012504592-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8778925-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016162472-A1 |
| priorityDate | 2005-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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