| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79fd7368d67744e318618b93144c74e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bb8b65410e011d12bcb389fae271222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d17421b65b2d77642835c00ebe53d56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61890b924812c36aeb98b77fb679cd55 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43595
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 |
| filingDate |
2006-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5761b016b746b45a1e3f3fad32f2611a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70164562ee39fcfa11e528393e86ece2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b82a510037cb4b2fe6b375ba5fe503bf |
| publicationDate |
2007-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007007199-A2 |
| titleOfInvention |
Fluorescent indicators of hydrogen peroxide and methods for using same |
| abstract |
The present invention provides a novel genetically encoded fluorescent indicator of hydrogen peroxide. The indicator comprises a sensor polypeptide which is responsive to hydrogen peroxide and a circularly permuted fluorescent protein which is operatively inserted into the sensor polypeptide. Interaction of the sensor polypeptide with hydrogen peroxide results in a change in fluorescence of the fluorescent protein. An isolated nucleic acid molecule encoding a hydrogen peroxide fluorescent indicator of the present invention is also provided. Also provided are vectors, expression cassettes, host-cells, stable cell lines, transgenic animals and transgenic plants comprising a nucleic acid of the present invention. Also provided are methods that use a fluorescent protein of the present invention or the nucleic acid encoding it. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2066803-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3778650-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105524175-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105646716-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2493260-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104163868-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9915670-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104163868-A |
| priorityDate |
2005-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |